Children signs of mono
The designation “mononucleosis” refers to an increase in a particular type of white blood cells (lymphocytes) in the bloodstream relative to the other white blood cells as a result of the EBV infection. If your child has signs of mono, your pediatrician might also notice that your child has an enlarged spleen, an enlarged liver, arthralgia (joint pain without swelling or other signs of arthritis), jaundice, many enlarged lymphocytes (atypical lymphocytosis) on a blood test, elevated liver function tests, and a positive mono spot test.
Mononucleosis is caused by the Epstein-Barr virus, a member of the herpes virus family. The disease develops if the virus is encountered for the first time at an age when the response of the body’s immune system is most vigorous (that is, during adolescence and early adult life). The peak incidence of the illness occurs around the ages of 15 and 17.

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